Recommendation on Design, Execution, and Reporting of Animal Atherosclerosis Studies
Published: July 20, 2017
- Animal studies are a foundation for defining mechanisms of atherosclerosis and potential drug targets in cardiovascular diseases.
- Similar studies designed and conducted with different animal models can give conflicting results, which limits the ability to extrapolate the results to understanding the human disease.
- This statement aims to serve as a how-to resource for researchers as they design, develop, conduct, and interpret animal studies.
Supporting Materials
- Commentary: The Importance of Translational Research in Atherosclerosis– Crosslinking Studies from "Bench" to "Bed" and "Bunch"-sides Approaches by Yoshihiro Kokubo, MD, PhD, FAHA, FACC, FESC, FESO
- Top Things to Know: Recommendation on Design, Execution, and Reporting of Animal Atherosclerosis Studies
- Full article in Circulation Research